Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p346 | (1) | WCRB2014

Does xenotoxicant-disrupted fetal sheep thyroid development persist into adulthood?

Filis Panagiotis , Ramona Lauma , Murray Graeme , Hombach-Klonisch Sabine , Klonisch Thomas , O'Shaughnessy Peter , Fowler Paul A

Introduction: A complex cocktail of poorly biodegradable chemicals is ubiquitous in the modern environment and exposure to such chemicals contributes to diseases including thyroid dysfunction. The thyroid gland regulates growth and function of multiple organs and we previously showed that exposure to xenotoxicants (via maternal grazing on sewage sludge fertilised pastures) disturbed fetal sheep thyroid development. Our aim here was to assess whether the effects seen in fetal s...